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Multiple electrodes are now a standard tool in neuroscience research that make it possible to study the simultaneous activity of several neurons in a given brain region or across different regions. The data from multi-electrode studies present important analysis challenges that must be resolved for optimal use of these neurophysiological measurements to answer questions about how the brain works.
The authors review statistical methods for the analysis of multiple neural spike-train data and discuss future challenges for methodology research.
Emery N Brown, Robert E Kass & Partha P Mitra
Nature Neuroscience 7, 456 – 461 (2004)
Published online: 27 April 2004; | doi:10.1038/nn1228