Spontaneous network activity in the form of Up and Down states plays an important role in the function of neural circuits and reflects intrinsic connectivity. Such cortical dynamics are shaped by genes, experience and intrinsic cellular properties and form the substrate upon which external stimuli and neuromodulation will impinge to determine cortical responses. Read the rest of this entry…

Preprint of the forthcoming book chapter ‘Extracellular spikes and current-source density’ featuring the numerical framework biophysics for the calculation of extracellular potentials from transmembrane currents in multi-compartment neuron models, using the line-source method (Holt & Koch, J Comp Neurosci 1999).

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LFPy is a Python package for calculation of extracellular potentials from multicompartment neuron models. It relies on the NEURON simulator and uses the Python interface it provides.

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