Phd position in high resolution quantitative optical imaging of neurometabolic and neurovascular coupling mechanisms.


Noninvasive functional neuroimaging tools are widely applied to study the human brain in action. However, the hemodynamic signals of the most extensively used methods are still not well understood. This joint EPFL and ETHZ PhD project aims at understanding the quantitative aspects of hemodynamic changes that occur in the brain. For this aim, novel multimodal high resolution optical imaging tools will be developed and applied in animal experiments.
The thesis project (3 years) will consist of the following tasks
1. Development and validation of quantitative spectroscopic optical imaging (Lausanne).
2. In-vivo experiments in the rat and data analysis (Zurich).
Applicants should have a strong interest and background in engineering and/or physics. Skills in animal experiments are not mandatory, however, the candidate must be open and interested in this part of the project. Please contact Prof. Bruno Weber (bweber@pharma.unizh.ch) or Prof. Christian Depeursinge (christian.depeursinge@epfl.ch).

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